Intraepithelial carcinoma (Bowen disease) - Carcinoma Intraepithelial (Galar Bowen)
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Tipiciúil tuiseal ― D’fhéadfaí mídhiagnóisiú a dhéanamh ar Carcinoma Intraepithelial (Galar Bowen) (Intraepithelial carcinoma (Bowen disease)) mar eachma nach bhfuil cos ar bolg le fada.
References
Is cineál ailse craicinn é Bowen's disease (BD) a thosaíonn i gciseal seachtrach an chraiceann (eipideirm) . Tá sé níos coitianta i Caucasians agus is minic a tharlaíonn sé i limistéir faoi lé solas na gréine, ach is féidir é a bheith le feiceáil in áiteanna eile freisin. Is gnách go dtaispeántar BD mar lot amháin. Is minic a fheictear BD mar chomhartha rabhaidh sula bhforbraítear cineál níos tromchúisí ailse craicinn. Chun BD a dhiagnóiseadh, bíonn dochtúirí ag brath go hiondúil ar shamplaí fíocháin a scrúdú faoi mhicreascóp (bithóipse) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease tionchar den chuid is mó ar dhaoine bána os cionn 60 bliain d'aois. Áirítear leis na príomhfhachtóirí riosca nochtadh fadtéarmach don ghrian, córas imdhíonachta lag, nochtadh arsanaic, agus ionfhabhtú HPV ar an gcraiceann. Tá cineálacha HPV 16, 18, 34, agus 48 nasctha le galar Bowen i limistéir ghiniúna. Níl rannpháirtíocht HPV i gcásanna neamhghiniúna chomh soiléir céanna.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
De ghnáth feictear é mar limistéar erythematous, scaly nó crusty áit ar bith ar an gcorp. Is é an suíomh is coitianta ná cosa níos ísle.
Is féidir é a leigheas trí roghanna cóireála éagsúla, mar shampla cryotherapy, curettage, rabhadh, teiripe fótadinimiciúil, nó briseadh an lesion.
○ Diagnóis agus Cóireáil
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy